Digital pathology will be the next paradigm. Instead of using traditional microscopy, a pathologist will interact with pictures on computer screens and conduct quantitative analysis to get a diagnosis. The storage and quick distribution of image data in pathology and other biomedical fields have been made possible by the fourth generation of virtual slide telepathology systems, also known as virtual microscopy and whole-slide imaging. Digital imaging has been used in several medical disciplines recently. Digital microscopy became a crucial diagnostic tool in surgical pathology as a result of advances in hard- and software technology.
Image Analysis In Digital Pathology
Numerous possible benefits of automatic image analysis include less interobserver difference, increased uniformity, and increased productivity. Furthermore, the wealth of knowledge included in WSI offers enormous prospects for the development and evaluation of novel, more efficient therapies that may completely transform the treatment of patients with cancer and other disorders.
3D Diagnosis In Pathology
The visual examination of hematoxylin and eosin stained picture slides using traditional two-dimensional (2D) microscopy has been the mainstay of the pathological classification of many forms of malignancies since the early 20th century8. Recent advances in cutting-edge microscopy platforms have made it possible to quickly capture three-dimensional (3D) images from tissue samples with a thickness of up to several millimeters, such as fluorescent light sheet microscopy.
Fluorescent In Situ Sequencing
The “omics” domains of genomics, transcriptomics, proteomics, metabolomics, interactomics, immunomics, and others have developed extraordinarily as a result of numerous techniques using high-throughput methodologies etc. Numerous genes, transcripts, and proteins can be simultaneously determined and analysed to yield hitherto unheard-of insights into the structure, control, and operation of biological systems.
Modern microscopes, which are constantly being improved, have been successfully developed by researchers in order to produce high resolution images and to clearly show the structures of various cell and tissue types. But when a 4-5 fold enlargement of human brain tissue was recorded with little deformation, a revolutionary notion was born.
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